Responsible for initiating, directing and executing scientific
research, development and manufacturing process strategies to
support new and existing products. Investigates the feasibility of
applying a wide variety of scientific principles and concepts to
potential inventions, products and problems. Plans and executes
laboratory research. Maintains broad knowledge of state-of-the art
principles and theories. Makes contributions to scientific
literature and conferences. Serves as an in-house and outside
consultant. May act as a spokesperson for corporate scientific
affairs and advise top management. Participates in development of
patent applications. Promotes and participates in the professional
development of scientists and laboratory facilities. Uses
professional concepts to contribute to the development of product
or process principles and to achieve objectives in creative and
Conceives, plans, designs and conducts advanced independent
research in compound, assay, process, product or method development
to support on-going production, continuous improvements and new
Receives general direction and exercises considerable discretion
as to work details.
Contributes to the definition and timely achievement of overall
Participates or leads in efforts to define new components,
products or processes.
Identifies and solves technical challenges.
Identifies and implements improvements to work processes.
Creates potentially patentable components for systems, reagents
Designs, plans and executes project related tasks.
Designs and executes experiments to test hypothesis related to
Applies advanced scientific knowledge to projects; determines
priorities for experiments.
Independently designs and executes experiments.
Utilizes DOE as appropriate.
Assures experimental quality through sound, independent,
Participates or leads cross functional technical teams such as a
failure investigation or core team.
Establishes interfaces across other organizational groups.
Provides technical direction and feedback to others.
Teaches others and troubleshoots problems.
Participates in project planning, process updates and
contributes to experimental design.
Prepares and delivers presentations of project results to
others; presents data to larger and more diverse
Monitors work to ensure quality, and continuously promote
Quality First Time.
Bachelors degree plus 10 years relevant experience OR
Masters Degree plus 5 years OR PhD and 2 years relevant
Strong background in structure-based protein analysis and
engineering. Experience with computational protein engineering and
antibody epitope modeling.
Experience with protein purification and characterization,
including HPLC, FPLC, immunoaffinity, SDS-PAGE, and WB.
Experience with mammalian cell culture and cell culture process
Domain knowledge in oncology, immunology, or neurology.
Demonstrated record of scientific accomplishment, with a history
of publications and presentations. Strong work ethic and
Excellent communication and leadership skills with a deep
commitment to working as part of teams and recognizing the
strengths of everyone on the team.
Knowledge, Skills and Abilities
Demonstrates success in technical proficiency, scientific
creativity, collaboration with others and independent thought.
Expert knowledge of scientific principles and concepts.
Applies advanced technical writing skills to produce reports and
documents; writes independently; evaluates the writing of
Preferred (valued) skills:
Experience with display technologies (yeast or phage).
Experience with cutting-edge biologics formats including bi- and
Experience with bio-orthogonal chemistry, probe development,
and/or proximity labeling techniques.
Experience with multi-color Flow Cytometry/sorting.
Roche is an equal opportunity employer and strictly prohibits
unlawful discrimination based upon an individual's race, color,
religion, gender, sexual orientation, gender identity/expression,
national origin/ancestry, age, mental/physical disability, medical
condition, marital status, veteran status, or any other
characteristic protected by law.
If you have a disability and need an accommodation in connection
with the on-line application process, please email us at