Principal Scientist I (PHC)
Company: Hoffmann-La Roche Ltd
Posted on: May 3, 2021
We are looking for an outstanding Principal Scientist in the
area of human diagnostic development and digital PCR. The main
responsibilities will include research and development in the areas
of novel reagents and protocols for automated nucleic acid
quantification, digital PCR, other molecular diagnostics assay
technologies, various analytical processes and methods as well as
participation in cross-functional projects across the entire
An advanced degree in Biology, Chemistry, Biochemistry, Chemical
Biology, or related fields, and relevant industry or post-doctoral
experience is highly preferred. The position requires a minimum of
8 years of research and development experience with a track record
of innovation and peer reviewed publications, and it is preferred
that the candidates have supervisory management experience in
leading small research teams.
The Principal Scientist will provide general expertise in
nucleic acid purification and amplification techniques, and
participate in development and evaluation of new technologies and
products. Hands-on experimental skills and demonstrated ability to
translate innovation into products or proof of concept are
required. The successful candidate will have leadership
responsibility in a development team and represent development
efforts in a cross-functional team. Experience in nucleic acid
extraction and amplification technologies, digital PCR methods and
analysis, and diagnostics is highly desirable.
Key Roles & Responsibilities
Aligns project and team goals with the company's business
Develops product concepts aligned with customer requirements and
product specifications, and translates them into focused scientific
Plans, designs, and executes advanced independent or
multi-disciplinary research/development experiments driven by
strategic business needs.
Manages projects and teams, provides scientific/technical
direction, and designates accountability for product research and
development activities. Gives people assignments and training to
develop their abilities.
Serves as a subject matter expert at various management levels.
Prepares timelines and assessments of project progress and critical
factors, and establishes priorities. Assumes responsibility for
timely completion of projects, and resolves technical issues.
Ensures activities meet performance/quality expectations and are
consistent with project critical path.
Ensures technical activities under delegated supervision are
conducted within of internal and external guidelines and
Interacts with other departments to further project goals.
Responsible for the transfer of prototype product technology and
documentation from Research to Development and/or to Manufacturing.
Provides information and assistance to other departments to support
product scale-up, manufacture, launch and sales.
Recommends new approaches, expansion or curtailment of project
technical activities based on experimental results or new
scientific information. Adjusts direction of research activities
accordingly as scientific findings warrant.
Communicates progress of efforts to Director and other
departments to assure awareness of current status of projects.
Provides top line review of experimental results, and secondary
review of experimental data. Prepares comprehensive written and
verbal project status reports, and written manuscripts for
publication in some cases. Presents findings or comprehensive
project status reviews at internal & external meetings. Applies
advanced technical writing skills to produce reports and
- Influences senior management decisions that have an impact on
business direction of the area. Makes decisions under consultative
direction that have an impact on business direction of the area.
Decisions have a long term effect on the objectives of the function
Bachelor's Degree in Biological/Life Sciences, Chemistry,
Biochemistry or related field. Plus 7 years relevant industry
Prefer Ph.D. with 8 -10 years relevant industry experience
- Experience in assay optimization, experimental design,
versatile laboratory practice, data analysis, and data and concept
Roche is an equal opportunity employer and strictly prohibits
unlawful discrimination based upon an individual's race, color,
religion, gender, sexual orientation, gender identity/expression,
national origin/ancestry, age, mental/physical disability, medical
condition, marital status, veteran status, or any other
characteristic protected by law.
If you have a disability and need an accommodation in connection
with the on-line application process, please email us at
Keywords: Hoffmann-La Roche Ltd, Pleasanton , Principal Scientist I (PHC), Other , Pleasanton, California
Didn't find what you're looking for? Search again!