Senior/Staff Scientist - Single Cell Product Development (P-2501)
Company: 10x Genomics
Posted on: May 11, 2022
About The Role
We are seeking an outstanding Scientist to join the New Product
Development (NPD) team and lead the product development and
technology transfer efforts on the next generation of 10x products.
This is a unique cross-disciplinary position that will work closely
with a variety of groups including Molecular Biology, Chemistry,
Computational Biology, QC, Manufacturing, and Marketing to develop
and validate reagents, consumables, and kits for the rapid
expansion of 10X's single-cell product portfolio. Candidates must
have a broad working knowledge of molecular biology and be able to
apply that knowledge independently and creatively toward the
development and improvement of novel single-cell products and their
QC/production methods. Previous industry experience in product
development or process engineering, and ability to analyze large
data sets is required. The successful applicant will have
exceptional attention to detail and the ability to meticulously
execute and analyze highly complex experiments.
Individuals applying for this position must be self-starters,
strategic thinkers, action driven, flexible in changing direction
and methods, thrive in a fast-paced environment, excel at managing
multiple priorities, succeed in communicating with all levels
within the organization and provide immediate contribution.
What You Will Be Doing
Lead the effort to define product Key Performance Indicators for
all single cell products
Design and conduct experiments to determine underlying reaction
mechanisms, cause and effect, failure modes, guard band studies and
optimization using DOE methodologies.
Conceive, develop, validate, and implement new QC methods to assess
reagent quality, emulsion chemistries, consumables, and kits
through a variety of analytical and functional tests.
Help build out our internal manufacturing and process development
infrastructure to improve our single cell products.
Development and optimization of novel reagents for applications
within the single-cell portfolio of products
Independently troubleshoot and resolve reagent formulation, QC, and
incoming material issues.
PhD or MS in Molecular Biology, Biochemistry, Genetics,
Microbiology, Cell biology, Analytical Chemistry, or related
5+ years (PhD) or 10+ years (MS) relevant Biotechnology industry
Deep understanding of and hands-on experience with a variety of NGS
library preparation workflows; single cell workflows strongly
Experience using statistical tools, such as JMP to analyze complex
data sets, create DOE experiments, and data trending.
Demonstrated success in developing and optimizing novel molecular
biology assays in an industry setting.
Experience developing and implementing novel QC methods to assess
reagent performance in both functional and orthogonal assays.
Ability to write SOPs and train others to successfully perform the
Exceptionally strong collaboration and communication skills.
NGS reagent and kit development experience as demonstrated by the
successful launch of a commercial product
Demonstrated success moving products from concept phase through
Hands-on experience with 10X single-cell products
Experience with automated liquid handling systems
Expertise in cell preparation, cell staining, and working with
Previous work with custom reagent vendors and setting up OEM
Previous experience supervising and/or mentoring junior staff
About 10x Genomics
At 10x Genomics, accelerating our understanding of biology is more
than a mission for us. It is a commitment. This is the century of
biology, and the breakthroughs we make now have the potential to
change the world.
We enable scientists to advance their research, allowing them to
address scientific questions they did not even know they could ask.
Our tools have enabled fundamental discoveries across biology
including cancer, immunology, and neuroscience.
Our teams are empowered and encouraged to follow their passions,
pursue new ideas, and perform at their best in an inclusive and
dynamic environment. We know that behind every scientific
breakthrough, there is a deep infrastructure of talented people
driving the life sciences industry and making it possible for
scientists and clinicians to make new strides. We are dedicated to
finding the very best person for every aspect of our work because
the innovations and discoveries that we enable together will lead
to better technologies, better treatments, and a better future.
Find out how you can make a 10x difference.
Individuals seeking employment at 10x Genomics are considered
without regards to race, color, religion, national origin, age,
sex, marital status, ancestry, physical or mental disability,
veteran status, gender identity, or sexual orientation, or any
other characteristic protected by applicable law.
10x does not accept unsolicited applicants submitted by third-party
recruiters or agencies. Any resume or application submitted to 10x
without a vendor agreement in place will be considered unsolicited
and property of 10x, and 10x will not pay a placement fee.
Keywords: 10x Genomics, Pleasanton , Senior/Staff Scientist - Single Cell Product Development (P-2501), Other , Pleasanton, California
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