Research Associate / Senior Research Associate - Cell Biology & Histology - Contractor (P-9000)

Company: 10x Genomics
Location: Pleasanton
Posted on: May 14, 2022

Job Description:

At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world.

We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience.

Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference.

About The Role

We are looking for an outstanding individual to join our Cell Biology and Applications team as a Research Associate. This person will interact with scientists and other associates from all across the company, and will generate (and obtain), process, characterize, and distribute high-quality biological samples for both internal and external consumption on an ongoing basis.

The ideal candidate will have an education background in one or more of the following disciplines: Histology, Pathology, Neurobiology, Developmental Biology, Cancer Biology, or similar fields. For this role, you should have at least 2+ years of relevant research experience in an academic or industrial setting. You will apply your skills and knowledge of histology and tissue biology to optimize and evaluate new methods for sample preparation.

You will have proficiency in general histology techniques such as tissue processing, tissue embedding, sectioning OCT/paraffin embedded tissues, slide preparation, and experience performing and optimizing staining techniques, including immunohistochemical procedures, for microscopic evaluation and quantitative image analysis. Awareness of RNA, DNA, and protein integrity when handling samples. Proficiency in brightfield and fluorescence imaging are also desired.

In addition to technical qualifications, you will be highly goal-oriented, able to generate and manage reagent/sample databases, organized, inquisitive, independent, collaborative, willing to learn new techniques, platforms, and concepts, and be able to thrive in an atmosphere of shifting demands and priorities.

What You Will Be Doing
Assist in the implementation and optimization of electronic sample and reagent inventory tracking systems
Acquire, and maintain an inventory of relevant biological and clinical tissue samples, spanning from fresh mouse tissue to preserved human tumor biopsies
Assist in the screening of tissues for quality, composition, and biological significance
Assist in the development and optimization of sample preparation procedures/protocols for tissue and single cell genomic assays.
Prepare and provide slides containing tissue sections to multiple product development teams, which includes responsibility for adhering to a tight schedule while maintaining exceptional quality
Advise and assist R&D scientists with histology experiments and methods
Assist in training other research associates, technicians, and scientists as required
Maintain cooperative, professional, and positive attitude when interacting with others internally and externally

To Be Successful In This Role, You Will Need
BS/MS in one of the following disciplines: Pathology, Neurobiology, Cancer biology, or similar
2+ years of hands-on tissue biology and histology experience in an academic or industrial setting
Experience with provisioning or processing animal models and human clinical samples (tissue, blood, biopsies, fresh frozen, fixed frozen, FFPE)
Experience in proper tissue processing: snap-freezing, formalin fixation, paraffin embedding
Experience with tissue sectioning: cryostat and/or microtome
Experience with immunohistochemistry (IHC), immunofluorescence (IF), in situ hybridization (ISH) and/or other histochemical stains
Meticulous attention to detail and strong record-keeping skills
Proficiency in standard molecular biology techniques and benchmarking of RNA and DNA quality from tissue samples
Desire to be part of a rapidly evolving organization, which requires flexibility and a willingness to take initiative, and learn new techniques and concepts
Committed to total customer satisfaction with outstanding interpersonal skills and professionalism

Additionally, We'd Like To See
Familiarity with various tissue types (human and model organisms) and pathological samples in neurobiology and/or cancer biology
Experience with brightfield and fluorescence imaging
Willingness to learn novel techniques and processes
HT or HTL certification preferred but not required

About 10x Genomics

At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world.

We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience.

Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference.

Individuals seeking employment at 10x Genomics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation, or any other characteristic protected by applicable law.

10x does not accept unsolicited applicants submitted by third-party recruiters or agencies. Any resume or application submitted to 10x without a vendor agreement in place will be considered unsolicited and property of 10x, and 10x will not pay a placement fee.

Keywords: 10x Genomics, Pleasanton , Research Associate / Senior Research Associate - Cell Biology & Histology - Contractor (P-9000), Other , Pleasanton, California